Angioedema (swelling) occurring in the absence of urticaria (hives) had been a rare inherited disorder until the discovery of a class of blood pressure medication (ACE-inhibitors). These medication have been identified as causing massive swelling (angioedema) in the absense of hives (urticaria)  very similar to the rare inherited form. Swelling usually occurs in the lips, tongue, and throat, but may occur in the bowels. This is very dangerous since the swelling may impede the ability to breath. There have been deaths reported under these circumstances.

If you have recurrent episodes of swelling, contact your allergist.

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